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Distinct Humoral and Cellular Immunity Induced by Alternating Prime-boost Vaccination Using Plasmid DNA and Live Viral Vector Vaccines Expressing the E Protein of Dengue Virus Type 2

BACKGROUND: Dengue virus, which belongs to the Flavivirus genus of the Flaviviridae family, causes fatal dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) with infection risk of 2.5 billion people worldwide. However, approved vaccines are still not available. Here, we explored the immun...

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Detalles Bibliográficos
Autores principales: George, Junu A., Eo, Seong Kug
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243001/
https://www.ncbi.nlm.nih.gov/pubmed/22194710
http://dx.doi.org/10.4110/in.2011.11.5.268