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Deficiency of Foxp3(+) Regulatory T Cells Exacerbates Autoimmune Arthritis by Altering the Synovial Proportions of CD4(+) T Cells and Dendritic Cells
BACKGROUND: CD4(+)Fop3(+) regulatory T cells (Tregs) are needed to maintain peripheral tolerance, but their role in the development of autoimmune arthritis is still debated. The present study was undertaken to investigate the mechanism by which Tregs influence autoimmune arthritis, using a mouse mod...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Association of Immunologists
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243004/ https://www.ncbi.nlm.nih.gov/pubmed/22194713 http://dx.doi.org/10.4110/in.2011.11.5.299 |