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Deficiency of Foxp3(+) Regulatory T Cells Exacerbates Autoimmune Arthritis by Altering the Synovial Proportions of CD4(+) T Cells and Dendritic Cells

BACKGROUND: CD4(+)Fop3(+) regulatory T cells (Tregs) are needed to maintain peripheral tolerance, but their role in the development of autoimmune arthritis is still debated. The present study was undertaken to investigate the mechanism by which Tregs influence autoimmune arthritis, using a mouse mod...

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Detalles Bibliográficos
Autores principales: Jang, Eunkyeong, Cho, Mi La, Oh, Hye-Joa, Youn, Jeehee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243004/
https://www.ncbi.nlm.nih.gov/pubmed/22194713
http://dx.doi.org/10.4110/in.2011.11.5.299