Unusually Strong Temperature Dependence of P2X3 Receptor Traffic to the Plasma Membrane

ATP-gated P2X3 receptors are expressed by nociceptive neurons and participate in transduction of pain. Responsiveness of P2X3 receptors is strongly reduced at low temperatures, suggesting a role for these receptors in analgesic effects of cooling. Since sustained responsiveness depends on receptor t...

Descripción completa

Detalles Bibliográficos
Autores principales: Pryazhnikov, E., Fayuk, D., Niittykoski, M., Giniatullin, Rashid, Khiroug, Leonard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243083/
https://www.ncbi.nlm.nih.gov/pubmed/22194716
http://dx.doi.org/10.3389/fncel.2011.00027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243083/
https://www.ncbi.nlm.nih.gov/pubmed/22194716
http://dx.doi.org/10.3389/fncel.2011.00027

Ejemplares similares