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Unusually Strong Temperature Dependence of P2X3 Receptor Traffic to the Plasma Membrane
ATP-gated P2X3 receptors are expressed by nociceptive neurons and participate in transduction of pain. Responsiveness of P2X3 receptors is strongly reduced at low temperatures, suggesting a role for these receptors in analgesic effects of cooling. Since sustained responsiveness depends on receptor t...
Autores principales: | Pryazhnikov, E., Fayuk, D., Niittykoski, M., Giniatullin, Rashid, Khiroug, Leonard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243083/ https://www.ncbi.nlm.nih.gov/pubmed/22194716 http://dx.doi.org/10.3389/fncel.2011.00027 |
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