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Exploration of structural stability in deleterious nsSNPs of the XPA gene: A molecular dynamics approach
BACKGROUND: Distinguishing the deleterious from the massive number of non-functional nsSNPs that occur within a single genome is a considerable challenge in mutation research. In this approach, we have used the existing in silico methods to explore the mutation-structure-function relationship in the...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243084/ https://www.ncbi.nlm.nih.gov/pubmed/22190868 http://dx.doi.org/10.4103/1477-3163.90441 |