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The Transcription Factor NURR1 Exerts Concentration-Dependent Effects on Target Genes Mediating Distinct Biological Processes

The transcription factor NURR1 plays a pivotal role in the development and maintenance of neurotransmitter phenotype in midbrain dopamine neurons. Conversely, decreased NURR1 expression is associated with a number of dopamine-related CNS disorders, including Parkinson’s disease and drug addiction. I...

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Detalles Bibliográficos
Autores principales: Johnson, Magen M., Michelhaugh, Sharon K., Bouhamdan, Mohamad, Schmidt, Carl J., Bannon, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243378/
https://www.ncbi.nlm.nih.gov/pubmed/22194714
http://dx.doi.org/10.3389/fnins.2011.00135