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Monocyte-specific Accessibility of a Matrix Attachment Region in the Tumor Necrosis Factor Locus

Regulation of TNF gene expression is cell type- and stimulus-specific. We have previously identified highly conserved noncoding regulatory elements within DNase I-hypersensitive sites (HSS) located 9 kb upstream (HSS−9) and 3 kb downstream (HSS+3) of the TNF gene, which play an important role in the...

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Detalles Bibliográficos
Autores principales: Biglione, Sebastian, Tsytsykova, Alla V., Goldfeld, Anne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243562/
https://www.ncbi.nlm.nih.gov/pubmed/22027829
http://dx.doi.org/10.1074/jbc.M111.272476