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Structural basis of initial RNA polymerase II transcription

During transcription initiation by RNA polymerase (Pol) II, a transient open promoter complex (OC) is converted to an initially transcribing complex (ITC) containing short RNAs, and to a stable elongation complex (EC). We report structures of a Pol II–DNA complex mimicking part of the OC, and of com...

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Detalles Bibliográficos
Autores principales: Cheung, Alan C M, Sainsbury, Sarah, Cramer, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243610/
https://www.ncbi.nlm.nih.gov/pubmed/22056778
http://dx.doi.org/10.1038/emboj.2011.396