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Dpb11 coordinates Mec1 kinase activation with cell cycle-regulated Rad9 recruitment

Eukaryotic cells respond to DNA damage by activating checkpoint signalling pathways. Checkpoint signals are transduced by a protein kinase cascade that also requires non-kinase mediator proteins. One such mediator is the Saccharomyces cerevisiae Dpb11 protein, which binds to and activates the apical...

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Detalles Bibliográficos
Autores principales: Pfander, Boris, Diffley, John F X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243626/
https://www.ncbi.nlm.nih.gov/pubmed/21946560
http://dx.doi.org/10.1038/emboj.2011.345