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Dpb11 coordinates Mec1 kinase activation with cell cycle-regulated Rad9 recruitment
Eukaryotic cells respond to DNA damage by activating checkpoint signalling pathways. Checkpoint signals are transduced by a protein kinase cascade that also requires non-kinase mediator proteins. One such mediator is the Saccharomyces cerevisiae Dpb11 protein, which binds to and activates the apical...
Autores principales: | Pfander, Boris, Diffley, John F X |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Molecular Biology Organization
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243626/ https://www.ncbi.nlm.nih.gov/pubmed/21946560 http://dx.doi.org/10.1038/emboj.2011.345 |
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