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Using Amino Acid Correlation and Community Detection Algorithms to Identify Functional Determinants in Protein Families

Correlated mutation analysis has a long history of interesting applications, mostly in the detection of contact pairs in protein structures. Based on previous observations that, if properly assessed, amino acid correlation data can also provide insights about functional sub-classes in a protein fami...

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Detalles Bibliográficos
Autores principales: Bleicher, Lucas, Lemke, Ney, Garratt, Richard Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243672/
https://www.ncbi.nlm.nih.gov/pubmed/22205928
http://dx.doi.org/10.1371/journal.pone.0027786