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Using Amino Acid Correlation and Community Detection Algorithms to Identify Functional Determinants in Protein Families
Correlated mutation analysis has a long history of interesting applications, mostly in the detection of contact pairs in protein structures. Based on previous observations that, if properly assessed, amino acid correlation data can also provide insights about functional sub-classes in a protein fami...
Autores principales: | Bleicher, Lucas, Lemke, Ney, Garratt, Richard Charles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243672/ https://www.ncbi.nlm.nih.gov/pubmed/22205928 http://dx.doi.org/10.1371/journal.pone.0027786 |
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