Mechanisms of MEOX1 and MEOX2 Regulation of the Cyclin Dependent Kinase Inhibitors p21(CIP1/WAF1) and p16(INK4a) in Vascular Endothelial Cells

Senescence, the state of permanent cell cycle arrest, has been associated with endothelial cell dysfunction and atherosclerosis. The cyclin dependent kinase inhibitors p21(CIP1/WAF1) and p16(INK4a) govern the G(1)/S cell cycle checkpoint and are essential for determining whether a cell enters into a...

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Detalles Bibliográficos
Autores principales: Douville, Josette M., Cheung, David Y. C., Herbert, Krista L., Moffatt, Teri, Wigle, Jeffrey T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243699/
https://www.ncbi.nlm.nih.gov/pubmed/22206000
http://dx.doi.org/10.1371/journal.pone.0029099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243699/
https://www.ncbi.nlm.nih.gov/pubmed/22206000
http://dx.doi.org/10.1371/journal.pone.0029099

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