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Coupled Motions Direct Electrons along Human Microsomal P450 Chains

Protein domain motion is often implicated in biological electron transfer, but the general significance of motion is not clear. Motion has been implicated in the transfer of electrons from human cytochrome P450 reductase (CPR) to all microsomal cytochrome P450s (CYPs). Our hypothesis is that tight c...

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Detalles Bibliográficos
Autores principales: Pudney, Christopher R., Khara, Basile, Johannissen, Linus O., Scrutton, Nigel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243717/
https://www.ncbi.nlm.nih.gov/pubmed/22205878
http://dx.doi.org/10.1371/journal.pbio.1001222