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Mechanotransduction In Vivo by Repeated Talin Stretch-Relaxation Events Depends upon Vinculin
Mechanotransduction is a critical function for cells, in terms of cell viability, shaping of tissues, and cellular behavior. In vitro, cellular level forces can stretch adhesion proteins that link extracellular matrix to the actin cytoskeleton exposing hidden binding sites. However, there is no evid...
Autores principales: | Margadant, Felix, Chew, Li Li, Hu, Xian, Yu, Hanry, Bate, Neil, Zhang, Xian, Sheetz, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243729/ https://www.ncbi.nlm.nih.gov/pubmed/22205879 http://dx.doi.org/10.1371/journal.pbio.1001223 |
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