Comparison of the Effects of Hexavalent Chromium in the Alimentary Canal of F344 Rats and B6C3F1 Mice Following Exposure in Drinking Water: Implications for Carcinogenic Modes of Action

Exposure to high concentrations of hexavalent chromium (Cr[VI]) in drinking water is reported to induce oral mucosa tumors in F344 rats and intestinal tumors in B6C3F1 mice. To investigate the modes of action underlying these tumors, 90-day drinking water studies (with interim necropsy at day 8) wer...

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Detalles Bibliográficos
Autores principales: Thompson, Chad M., Proctor, Deborah M., Suh, Mina, Haws, Laurie C., Hébert, Charles D., Mann, Jill F., Shertzer, Howard G., Hixon, J. Gregory, Harris, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Environmental Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243750/
https://www.ncbi.nlm.nih.gov/pubmed/22011396
http://dx.doi.org/10.1093/toxsci/kfr280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243750/
https://www.ncbi.nlm.nih.gov/pubmed/22011396
http://dx.doi.org/10.1093/toxsci/kfr280

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