Sox2 maintains self-renewal of tumor initiating cells in osteosarcomas

Tumors are thought to be sustained by a reservoir of self-renewing cells, termed tumor initiating cells or cancer stem cells. Osteosarcomas are high-grade sarcomas derived from osteoblast progenitor cells and are the most common pediatric bone malignancy. In this report we show that the stem cell tr...

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Detalles Bibliográficos
Autores principales: Basu-Roy, Upal, Seo, Eunjeong, Ramanathapuram, Lalitha, Rapp, Timothy B., Perry, Jennifer A., Orkin, Stuart H., Mansukhani, Alka, Basilico, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243769/
https://www.ncbi.nlm.nih.gov/pubmed/21927024
http://dx.doi.org/10.1038/onc.2011.405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243769/
https://www.ncbi.nlm.nih.gov/pubmed/21927024
http://dx.doi.org/10.1038/onc.2011.405

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