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Structural Features of Antiviral APOBEC3 Proteins are Linked to Their Functional Activities
Human APOBEC3 (A3) proteins are cellular cytidine deaminases that potently restrict the replication of retroviruses by hypermutating viral cDNA and/or inhibiting reverse transcription. There are seven members of this family including A3A, B, C, DE, F, G, and H, all encoded in a tandem array on human...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Research Foundation
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243911/ https://www.ncbi.nlm.nih.gov/pubmed/22203821 http://dx.doi.org/10.3389/fmicb.2011.00258 |