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Knockout of ERK5 causes multiple defects in placental and embryonic development

BACKGROUD: ERK5 is a member of the mitogen activated protein kinase family activated by certain mitogenic or stressful stimuli in cells, but whose physiological role is largely unclear. RESULTS: To help determine the function of ERK5 we have used gene targeting to inactivate this gene in mice. Here...

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Detalles Bibliográficos
Autores principales: Yan, Lijun, Carr, Julia, Ashby, Peter R, Murry-Tait, Victoria, Thompson, Calum, Arthur, J Simon C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC324396/
https://www.ncbi.nlm.nih.gov/pubmed/14675480
http://dx.doi.org/10.1186/1471-213X-3-11