Cargando…
Autophagy in antigen-presenting cells results in presentation of citrullinated peptides to CD4 T cells
Antibody responses to citrullinated self-proteins are found in autoimmunities, particularly in rheumatoid arthritis, where they serve as a diagnostic indicator. We show here that processing of the protein hen egg-white lysozyme (HEL) resulted in citrullination of peptides presented on class II MHC m...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244027/ https://www.ncbi.nlm.nih.gov/pubmed/22162830 http://dx.doi.org/10.1084/jem.20110640 |