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Autophagy in antigen-presenting cells results in presentation of citrullinated peptides to CD4 T cells

Antibody responses to citrullinated self-proteins are found in autoimmunities, particularly in rheumatoid arthritis, where they serve as a diagnostic indicator. We show here that processing of the protein hen egg-white lysozyme (HEL) resulted in citrullination of peptides presented on class II MHC m...

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Detalles Bibliográficos
Autores principales:	Ireland, Jamie M., Unanue, Emil R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2011
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244027/ https://www.ncbi.nlm.nih.gov/pubmed/22162830 http://dx.doi.org/10.1084/jem.20110640

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