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TAK1 in brain endothelial cells mediates fever and lethargy

Systemic inflammation affects the brain, resulting in fever, anorexia, lethargy, and activation of the hypothalamus–pituitary–adrenal axis. How peripheral inflammatory signals reach the brain is still a matter of debate. One possibility is that, in response to inflammatory stimuli, brain endothelial...

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Detalles Bibliográficos
Autores principales: Ridder, Dirk A., Lang, Ming-Fei, Salinin, Sergei, Röderer, Jan-Peter, Struss, Marcel, Maser-Gluth, Christiane, Schwaninger, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244031/
https://www.ncbi.nlm.nih.gov/pubmed/22143887
http://dx.doi.org/10.1084/jem.20110398