Cargando…

TAK1 in brain endothelial cells mediates fever and lethargy

Systemic inflammation affects the brain, resulting in fever, anorexia, lethargy, and activation of the hypothalamus–pituitary–adrenal axis. How peripheral inflammatory signals reach the brain is still a matter of debate. One possibility is that, in response to inflammatory stimuli, brain endothelial...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ridder, Dirk A., Lang, Ming-Fei, Salinin, Sergei, Röderer, Jan-Peter, Struss, Marcel, Maser-Gluth, Christiane, Schwaninger, Markus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2011
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244031/ https://www.ncbi.nlm.nih.gov/pubmed/22143887 http://dx.doi.org/10.1084/jem.20110398

Ejemplares similares

Brain endothelial TAK1 and NEMO safeguard the neurovascular unit
por: Ridder, Dirk A., et al.
Publicado: (2015)

Intussusception Presenting with Malignant Hypertension and Lethargy
por: de Vries, Andra, et al.
Publicado: (2013)

Adult hypopituitarism: Are we missing or is it clinical lethargy?
por: Brar, K. S., et al.
Publicado: (2011)

The endothelial basement membrane acts as a checkpoint for entry of pathogenic T cells into the brain
por: Zhang, Xueli, et al.
Publicado: (2020)

The surface-anchored NanA protein promotes pneumococcal brain endothelial cell invasion
por: Uchiyama, Satoshi, et al.
Publicado: (2009)

Endothelial Rbpj deletion normalizes Notch4-induced brain arteriovenous malformation in mice
por: Nielsen, Corinne M., et al.
Publicado: (2022)

Angiotensin II impairs endothelial function via tyrosine phosphorylation of the endothelial nitric oxide synthase
por: Loot, Annemarieke E., et al.
Publicado: (2009)

Endothelial cell–specific lymphotoxin-β receptor signaling is critical for lymph node and high endothelial venule formation
por: Onder, Lucas, et al.
Publicado: (2013)

Cases of Apoplexy and Lethargy; with Observations upon the Comatose Diseases
Publicado: (1812)

Acute lethargy, stridor, and hypoxemia in a young adult
por: Barnicle, Ryan N., et al.
Publicado: (2023)

Endothelial Cell “Memory” of Inflammatory Stimulation: Human Venular Endothelial Cells Store Interleukin 8 in Weibel-Palade Bodies
por: Wolff, Barbara, et al.
Publicado: (1998)

Endothelial mTOR maintains hematopoiesis during aging
por: Ramalingam, Pradeep, et al.
Publicado: (2020)

Homozygous deletion in MICU1 presenting with fatigue and lethargy in childhood
por: Lewis-Smith, David, et al.
Publicado: (2016)

17-Month-Old Girl With Severe, Prolonged Lethargy and Somnolence
por: Lure, Allison C, et al.
Publicado: (2021)

GIMAP5 maintains liver endothelial cell homeostasis and prevents portal hypertension
por: Drzewiecki, Kaela, et al.
Publicado: (2021)

Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever live attenuated vaccine
por: Bastard, Paul, et al.
Publicado: (2021)

Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning
por: Pham, Trung H.M., et al.
Publicado: (2010)

Live attenuated yellow fever 17D infects human DCs and allows for presentation of endogenous and recombinant T cell epitopes
por: Barba-Spaeth, Giovanna, et al.
Publicado: (2005)

Rapid Secretion of Prestored Interleukin 8 from Weibel-Palade Bodies of Microvascular Endothelial Cells
por: Utgaard, Jon Olav, et al.
Publicado: (1998)

Rapamycin antagonizes TNF induction of VCAM-1 on endothelial cells by inhibiting mTORC2
por: Wang, Chen, et al.
Publicado: (2014)

The Ccr7 Ligand ELC (Ccl19) Is Transcytosed in High Endothelial Venules and Mediates T Cell Recruitment
por: Baekkevold, Espen S., et al.
Publicado: (2001)

New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling
por: Dik, Willem A., et al.
Publicado: (2005)

Vascular Endothelial Growth Factor Can Substitute for Macrophage Colony-Stimulating Factor in the Support of Osteoclastic Bone Resorption
por: Niida, Shumpei, et al.
Publicado: (1999)

Human KIT(+) myeloid cells facilitate visceral metastasis by melanoma
por: Yu, Chun I., et al.
Publicado: (2021)

Hepatic Endothelial CCL25 Mediates the Recruitment of CCR9(+) Gut-homing Lymphocytes to the Liver in Primary Sclerosing Cholangitis
por: Eksteen, Bertus, et al.
Publicado: (2004)

Destruction of tumor vasculature and abated tumor growth upon VEGF blockade is driven by proapoptotic protein Bim in endothelial cells
por: Naik, Edwina, et al.
Publicado: (2011)

Lymph node–resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation
por: Cohen, Jarish N., et al.
Publicado: (2010)

Relation between time and kinetic energy in a constant lethargy system
por: Rubbia, Carlo, et al.
Publicado: (1995)

Lethargy and quadraparesis as initial manifestations of covid-19 child: Case report
por: Hammed, Ali, et al.
Publicado: (2022)

Alu elements mediate MYB gene tandem duplication in human T-ALL
por: O'Neil, Jennifer, et al.
Publicado: (2007)

Computer Vision Applied to Detect Lethargy through Animal Motion Monitoring: A Trial on African Swine Fever in Wild Boar
por: Fernández-Carrión, Eduardo, et al.
Publicado: (2020)

The calcium sensor STIM1 is an essential mediator of arterial thrombosis and ischemic brain infarction
por: Varga-Szabo, David, et al.
Publicado: (2008)

Nuclear Factor (NF)-κB–regulated X-chromosome–linked iap Gene Expression Protects Endothelial Cells from Tumor Necrosis Factor α–induced Apoptosis
por: Stehlik, Christian, et al.
Publicado: (1998)

Direct in vivo V(H) to J(H) rearrangement violating the 12/23 rule
por: Koralov, Sergei B., et al.
Publicado: (2005)

Unilateral thalamic infarction onset with lethargy: A case report and literature review
por: Kong, Wei, et al.
Publicado: (2022)

Negative selection, not receptor editing, is a physiological response of autoreactive thymocytes
por: Kreslavsky, Taras, et al.
Publicado: (2013)

Intracellular Adenosine Triphosphate (ATP) Concentration: A Switch in the Decision Between Apoptosis and Necrosis
por: Leist, Marcel, et al.
Publicado: (1997)

A Skin Homing Molecule Defines the Langerhans Cell Progenitor in Human Peripheral Blood
por: Strunk, Dirk, et al.
Publicado: (1997)

Hypoxia–Reoxygenation Triggers Coronary Vasospasm in Isolated Bovine Coronary Arteries via Tyrosine Nitration of Prostacyclin Synthase
por: Zou, Ming-Hui, et al.
Publicado: (1999)

IL-4–producing CD4(+) T cells in reactive lymph nodes during helminth infection are T follicular helper cells
por: King, Irah L., et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_39hskbld9f1cbbdhgrtm9fuohs