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Guanylate binding protein 1 is a novel effector of EGFR-driven invasion in glioblastoma
Although GBP1 (guanylate binding protein 1) was among the first interferon-inducible proteins identified, its function is still largely unknown. Epidermal growth factor receptor (EGFR) activation by amplification or mutation is one of the most frequent genetic lesions in a variety of human tumors. T...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244036/ https://www.ncbi.nlm.nih.gov/pubmed/22162832 http://dx.doi.org/10.1084/jem.20111102 |