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A small CD11b(+) human B1 cell subpopulation stimulates T cells and is expanded in lupus
A primary function of B lymphocytes is immunoglobulin production; however, the therapeutic benefit of B cell depletion in autoimmune diseases previously thought to be T cell mediated suggests that some B cells fulfill other roles in autoimmunity. We examined the recently identified human B1 cell pop...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Rockefeller University Press
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244038/ https://www.ncbi.nlm.nih.gov/pubmed/22110167 http://dx.doi.org/10.1084/jem.20110978 |