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A Simple Negative Interaction in the Positive Transcriptional Feedback of a Single Gene Is Sufficient to Produce Reliable Oscillations

Negative and positive transcriptional feedback loops are present in natural and synthetic genetic oscillators. A single gene with negative transcriptional feedback needs a time delay and sufficiently strong nonlinearity in the transmission of the feedback signal in order to produce biochemical rhyth...

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Detalles Bibliográficos
Autores principales: Miró-Bueno, Jesús M., Rodríguez-Patón, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244268/
https://www.ncbi.nlm.nih.gov/pubmed/22205920
http://dx.doi.org/10.1371/journal.pone.0027414