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Systematic Drug Repositioning Based on Clinical Side-Effects
Drug repositioning helps fully explore indications for marketed drugs and clinical candidates. Here we show that the clinical side-effects (SEs) provide a human phenotypic profile for the drug, and this profile can suggest additional disease indications. We extracted 3,175 SE-disease relationships b...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244383/ https://www.ncbi.nlm.nih.gov/pubmed/22205936 http://dx.doi.org/10.1371/journal.pone.0028025 |