The Plasmodium falciparum Malaria M1 Alanyl Aminopeptidase (PfA-M1): Insights of Catalytic Mechanism and Function from MD Simulations

Malaria caused by several species of Plasmodium is major parasitic disease of humans, causing 1–3 million deaths worldwide annually. The widespread resistance of the human parasite to current drug therapies is of major concern making the identification of new drug targets urgent. While the parasite...

Descripción completa

Detalles Bibliográficos
Autores principales: Jones, Peter M., Robinson, Mark W., Dalton, John P., George, Anthony M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244404/
https://www.ncbi.nlm.nih.gov/pubmed/22205955
http://dx.doi.org/10.1371/journal.pone.0028589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244404/
https://www.ncbi.nlm.nih.gov/pubmed/22205955
http://dx.doi.org/10.1371/journal.pone.0028589

Ejemplares similares