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The Plasmodium falciparum Malaria M1 Alanyl Aminopeptidase (PfA-M1): Insights of Catalytic Mechanism and Function from MD Simulations
Malaria caused by several species of Plasmodium is major parasitic disease of humans, causing 1–3 million deaths worldwide annually. The widespread resistance of the human parasite to current drug therapies is of major concern making the identification of new drug targets urgent. While the parasite...
Autores principales: | Jones, Peter M., Robinson, Mark W., Dalton, John P., George, Anthony M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244404/ https://www.ncbi.nlm.nih.gov/pubmed/22205955 http://dx.doi.org/10.1371/journal.pone.0028589 |
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