Selective Cytotoxicity against Human Osteosarcoma Cells by a Novel Synthetic C-1 Analogue of 7-Deoxypancratistatin Is Potentiated by Curcumin

The natural compound pancratistatin (PST) is a non-genotoxic inducer of apoptosis in a variety of cancers. It exhibits cancer selectivity as non-cancerous cells are markedly less sensitive to PST. Nonetheless, PST is not readily synthesized and is present in very low quantities in its natural source...

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Detalles Bibliográficos
Autores principales: Ma, Dennis, Tremblay, Phillip, Mahngar, Kevinjeet, Collins, Jonathan, Hudlicky, Tomas, Pandey, Siyaram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244407/
https://www.ncbi.nlm.nih.gov/pubmed/22205968
http://dx.doi.org/10.1371/journal.pone.0028780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244407/
https://www.ncbi.nlm.nih.gov/pubmed/22205968
http://dx.doi.org/10.1371/journal.pone.0028780

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