Accounting for Population Stratification in Practice: A Comparison of the Main Strategies Dedicated to Genome-Wide Association Studies

Genome-Wide Association Studies are powerful tools to detect genetic variants associated with diseases. Their results have, however, been questioned, in part because of the bias induced by population stratification. This is a consequence of systematic differences in allele frequencies due to the dif...

Descripción completa

Detalles Bibliográficos
Autores principales: Bouaziz, Matthieu, Ambroise, Christophe, Guedj, Mickael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244428/
https://www.ncbi.nlm.nih.gov/pubmed/22216125
http://dx.doi.org/10.1371/journal.pone.0028845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244428/
https://www.ncbi.nlm.nih.gov/pubmed/22216125
http://dx.doi.org/10.1371/journal.pone.0028845

Ejemplares similares