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EB1 Is Required for Spindle Symmetry in Mammalian Mitosis

Most information about the roles of the adenomatous polyposis coli protein (APC) and its binding partner EB1 in mitotic cells has come from siRNA studies. These suggest functions in chromosomal segregation and spindle positioning whose loss might contribute to tumourigenesis in cancers initiated by...

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Detalles Bibliográficos
Autores principales: Brüning-Richardson, Anke, Langford, Kelly J., Ruane, Peter, Lee, Tracy, Askham, Jon M., Morrison, Ewan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244432/
https://www.ncbi.nlm.nih.gov/pubmed/22216133
http://dx.doi.org/10.1371/journal.pone.0028884