Comparison of IRES and F2A-Based Locus-Specific Multicistronic Expression in Stable Mouse Lines

Efficient and stoichiometric expression of genes concatenated by bi- or multi-cistronic vectors has become an invaluable tool not only in basic biology to track and visualize proteins in vivo, but also for vaccine development and in the clinics for gene therapy. To adequately compare, in vivo, the e...

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Detalles Bibliográficos
Autores principales: Chan, Hsiao Yun, Sivakamasundari, Xing, Xing, Kraus, Petra, Yap, Sook Peng, Ng, Patricia, Lim, Siew Lan, Lufkin, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244433/
https://www.ncbi.nlm.nih.gov/pubmed/22216134
http://dx.doi.org/10.1371/journal.pone.0028885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244433/
https://www.ncbi.nlm.nih.gov/pubmed/22216134
http://dx.doi.org/10.1371/journal.pone.0028885

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