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Comparison of IRES and F2A-Based Locus-Specific Multicistronic Expression in Stable Mouse Lines
Efficient and stoichiometric expression of genes concatenated by bi- or multi-cistronic vectors has become an invaluable tool not only in basic biology to track and visualize proteins in vivo, but also for vaccine development and in the clinics for gene therapy. To adequately compare, in vivo, the e...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244433/ https://www.ncbi.nlm.nih.gov/pubmed/22216134 http://dx.doi.org/10.1371/journal.pone.0028885 |