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Non-cell-autonomous RNA interference in mammalian cells: Implications for in vivo cell-based RNAi delivery
RNA interference (RNAi) is a post-transcriptional pathway in which double-stranded RNA (dsRNA) triggers the degradation of complementary mRNA in the cytoplasm of eukaryotic cells. In plants and in some animals, including Caenorhabditis elegans, initiation of RNAi in one cell can lead to sequence-spe...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Library Publishing Media
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244743/ https://www.ncbi.nlm.nih.gov/pubmed/22205888 |