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Non-cell-autonomous RNA interference in mammalian cells: Implications for in vivo cell-based RNAi delivery

RNA interference (RNAi) is a post-transcriptional pathway in which double-stranded RNA (dsRNA) triggers the degradation of complementary mRNA in the cytoplasm of eukaryotic cells. In plants and in some animals, including Caenorhabditis elegans, initiation of RNAi in one cell can lead to sequence-spe...

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Detalles Bibliográficos
Autores principales: Cohen, Hannah C, Xiong, May P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Library Publishing Media 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244743/
https://www.ncbi.nlm.nih.gov/pubmed/22205888