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A robust clustering algorithm for identifying problematic samples in genome-wide association studies

Summary: High-throughput genotyping arrays provide an efficient way to survey single nucleotide polymorphisms (SNPs) across the genome in large numbers of individuals. Downstream analysis of the data, for example in genome-wide association studies (GWAS), often involves statistical models of genotyp...

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Detalles Bibliográficos
Autores principales: Bellenguez, Céline, Strange, Amy, Freeman, Colin, Donnelly, Peter, Spencer, Chris C.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244763/
https://www.ncbi.nlm.nih.gov/pubmed/22057162
http://dx.doi.org/10.1093/bioinformatics/btr599