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COLT-Cancer: functional genetic screening resource for essential genes in human cancer cell lines

Genome-wide pooled shRNA screens enable global identification of the genes essential for cancer cell survival and proliferation and provide a ‘functional genetic’ map of human cancer to complement genomic studies. Using a lentiviral shRNA library targeting approximately 16 000 human genes and a newl...

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Detalles Bibliográficos
Autores principales: Koh, Judice L. Y., Brown, Kevin R., Sayad, Azin, Kasimer, Dahlia, Ketela, Troy, Moffat, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245009/
https://www.ncbi.nlm.nih.gov/pubmed/22102578
http://dx.doi.org/10.1093/nar/gkr959