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COLT-Cancer: functional genetic screening resource for essential genes in human cancer cell lines
Genome-wide pooled shRNA screens enable global identification of the genes essential for cancer cell survival and proliferation and provide a ‘functional genetic’ map of human cancer to complement genomic studies. Using a lentiviral shRNA library targeting approximately 16 000 human genes and a newl...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245009/ https://www.ncbi.nlm.nih.gov/pubmed/22102578 http://dx.doi.org/10.1093/nar/gkr959 |