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Protein Kinase A Regulates Molecular Chaperone Transcription and Protein Aggregation
Heat shock factor 1 (HSF1) regulates one of the major pathways of protein quality control and is essential for deterrence of protein-folding disorders, particularly in neuronal cells. However, HSF1 activity declines with age, a change that may open the door to progression of neurodegenerative disord...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245242/ https://www.ncbi.nlm.nih.gov/pubmed/22216146 http://dx.doi.org/10.1371/journal.pone.0028950 |