Zinc Deficiency Leads to Lipofuscin Accumulation in the Retinal Pigment Epithelium of Pigmented Rats

BACKGROUND: Age-related macular degeneration (AMD) is associated with lipofuscin accumulation whereas the content of melanosomes decreases. Melanosomes are the main storage of zinc in the pigmented tissues. Since the elderly population, as the most affected group for AMD, is prone to zinc deficit, w...

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Detalles Bibliográficos
Autores principales: Julien, Sylvie, Biesemeier, Antje, Kokkinou, Despina, Eibl, Oliver, Schraermeyer, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245262/
https://www.ncbi.nlm.nih.gov/pubmed/22216222
http://dx.doi.org/10.1371/journal.pone.0029245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245262/
https://www.ncbi.nlm.nih.gov/pubmed/22216222
http://dx.doi.org/10.1371/journal.pone.0029245

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