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Identification and Functional Characterization of Novel Phosphorylation Sites in TAK1-Binding Protein (TAB) 1

TAB1 was defined as a regulatory subunit of the protein kinase TAK1, which functions upstream in the pathways activated by interleukin (IL)-1, tumor necrosis factor (TNF), toll-like receptors (TLRs) and stressors. However, TAB1 also functions in the p38 MAPK pathway downstream of TAK1. We identified...

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Detalles Bibliográficos
Autores principales: Wolf, Alexander, Beuerlein, Knut, Eckart, Christoph, Weiser, Hendrik, Dickkopf, Beate, Müller, Helmut, Sakurai, Hiroaki, Kracht, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245275/
https://www.ncbi.nlm.nih.gov/pubmed/22216226
http://dx.doi.org/10.1371/journal.pone.0029256