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Heregulin β-1 Induces Loss of Cell-Cell Contact and Enhances Expression of MUC1 at the Cell Surface in HCC2998 and MKN45-1 Cells

Signal transduction and cell responses after stimulation with heregulin β-1 (HRG) are examined in HCC2998 and MKN45-1 cells, which have been used for a model system to study the formation of signet ring carcinomas, one of poorly differentiated adenocarcinomas. HRG stimulation causes rounding of the...

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Detalles Bibliográficos
Autores principales: Okoshi, Rintaro, Shu, Chung-Li, Ihara, Sayoko, Fukui, Yasuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245292/
https://www.ncbi.nlm.nih.gov/pubmed/22216327
http://dx.doi.org/10.1371/journal.pone.0029599