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Joint Ancestry and Association Testing in Admixed Individuals

For samples of admixed individuals, it is possible to test for both ancestry effects via admixture mapping and genotype effects via association mapping. Here, we describe a joint test called BMIX that combines admixture and association statistics at single markers. We first perform high-density admi...

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Detalles Bibliográficos
Autores principales: Shriner, Daniel, Adeyemo, Adebowale, Rotimi, Charles N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245293/
https://www.ncbi.nlm.nih.gov/pubmed/22216000
http://dx.doi.org/10.1371/journal.pcbi.1002325