Combinatorial Binding in Human and Mouse Embryonic Stem Cells Identifies Conserved Enhancers Active in Early Embryonic Development

Transcription factors are proteins that regulate gene expression by binding to cis-regulatory sequences such as promoters and enhancers. In embryonic stem (ES) cells, binding of the transcription factors OCT4, SOX2 and NANOG is essential to maintain the capacity of the cells to differentiate into an...

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Detalles Bibliográficos
Autores principales: Göke, Jonathan, Jung, Marc, Behrens, Sarah, Chavez, Lukas, O'Keeffe, Sean, Timmermann, Bernd, Lehrach, Hans, Adjaye, James, Vingron, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245296/
https://www.ncbi.nlm.nih.gov/pubmed/22215994
http://dx.doi.org/10.1371/journal.pcbi.1002304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245296/
https://www.ncbi.nlm.nih.gov/pubmed/22215994
http://dx.doi.org/10.1371/journal.pcbi.1002304

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