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Acute Multiple Organ Failure in Adult Mice Deleted for the Developmental Regulator Wt1

There is much interest in the mechanisms that regulate adult tissue homeostasis and their relationship to processes governing foetal development. Mice deleted for the Wilms' tumour gene, Wt1, lack kidneys, gonads, and spleen and die at mid-gestation due to defective coronary vasculature. Wt1 is...

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Detalles Bibliográficos
Autores principales: Chau, You-Ying, Brownstein, David, Mjoseng, Heidi, Lee, Wen-Chin, Buza-Vidas, Natalija, Nerlov, Claus, Jacobsen, Sten Eirik, Perry, Paul, Berry, Rachel, Thornburn, Anna, Sexton, David, Morton, Nik, Hohenstein, Peter, Freyer, Elisabeth, Samuel, Kay, van't Hof, Rob, Hastie, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245305/
https://www.ncbi.nlm.nih.gov/pubmed/22216009
http://dx.doi.org/10.1371/journal.pgen.1002404