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Ce-Duox1/BLI-3 Generated Reactive Oxygen Species Trigger Protective SKN-1 Activity via p38 MAPK Signaling during Infection in C. elegans

Infected animals will produce reactive oxygen species (ROS) and other inflammatory molecules that help fight pathogens, but can inadvertently damage host tissue. Therefore specific responses, which protect and repair against the collateral damage caused by the immune response, are critical for succe...

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Detalles Bibliográficos
Autores principales: van der Hoeven, Ransome, McCallum, Katie C., Cruz, Melissa R., Garsin, Danielle A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245310/
https://www.ncbi.nlm.nih.gov/pubmed/22216003
http://dx.doi.org/10.1371/journal.ppat.1002453