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HMGA1 drives stem cell, inflammatory pathway, and cell cycle progression genes during lymphoid tumorigenesis

BACKGROUND: Although the high mobility group A1 (HMGA1) gene is widely overexpressed in diverse cancers and portends a poor prognosis in some tumors, the molecular mechanisms that mediate its role in transformation have remained elusive. HMGA1 functions as a potent oncogene in cultured cells and ind...

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Detalles Bibliográficos
Autores principales: Schuldenfrei, Andrew, Belton, Amy, Kowalski, Jeanne, Talbot, C Conover, Di Cello, Francescopaolo, Poh, Weijie, Tsai, Hua-Ling, Shah, Sandeep N, Huso, Tait H, Huso, David L, Resar, Linda MS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245506/
https://www.ncbi.nlm.nih.gov/pubmed/22053823
http://dx.doi.org/10.1186/1471-2164-12-549