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Three-dimensional modeling of chromatin structure from interaction frequency data using Markov chain Monte Carlo sampling

BACKGROUND: Long-range interactions between regulatory DNA elements such as enhancers, insulators and promoters play an important role in regulating transcription. As chromatin contacts have been found throughout the human genome and in different cell types, spatial transcriptional control is now vi...

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Detalles Bibliográficos
Autores principales: Rousseau, Mathieu, Fraser, James, Ferraiuolo, Maria A, Dostie, Josée, Blanchette, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245522/
https://www.ncbi.nlm.nih.gov/pubmed/22026390
http://dx.doi.org/10.1186/1471-2105-12-414