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Unscrambling an egg: protein disaggregation by AAA+ proteins

A protein quality control system, consisting of molecular chaperones and proteases, controls the folding status of proteins and prevents the aggregation of misfolded proteins by either refolding or degrading aggregation-prone species. During severe stress conditions this protection system can be ove...

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Detalles Bibliográficos
Autores principales: Weibezahn, Jimena, Bukau, Bernd, Mogk, Axel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC324561/
https://www.ncbi.nlm.nih.gov/pubmed/14728719
http://dx.doi.org/10.1186/1475-2859-3-1