Mutability of prions

Murine prions transferred from brain to cultured cells gradually adapt to the new environment. Brain-derived 22L prions can infect neuroblastoma-derived PK1 cells in the presence of swainsonine (swa); that is, they are ‘swa resistant’. PK1 cell-adapted 22L prions are swa sensitive; however, propagat...

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Detalles Bibliográficos
Autores principales: Li, Jiali, Mahal, Sukhvir P, Demczyk, Cheryl A, Weissmann, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2011
Materias:
Scientific Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245691/
https://www.ncbi.nlm.nih.gov/pubmed/21997293
http://dx.doi.org/10.1038/embor.2011.191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245691/
https://www.ncbi.nlm.nih.gov/pubmed/21997293
http://dx.doi.org/10.1038/embor.2011.191

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