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Floor plate-derived dopamine neurons from hESCs efficiently engraft in animal models of PD

Human pluripotent stem cells (hPSCs) are a promising source of cells for applications in regenerative medicine. Directed differentiation of hPSCs into specialized cells such as spinal motoneurons(1) or midbrain dopamine (DA) neurons(2) has been achieved. However, the effective use of hPSCs for cell...

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Detalles Bibliográficos
Autores principales: Kriks, Sonja, Shim, Jae-Won, Piao, Jinghua, Ganat, Yosif M., Wakeman, Dustin R., Xie, Zhong, Carrillo-Reid, Luis, Auyeung, Gordon, Antonacci, Chris, Buch, Amanda, Yang, Lichuan, Beal, M. Flint, Surmeier, D. James, Kordower, Jeffrey H., Tabar, Viviane, Studer, Lorenz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245796/
https://www.ncbi.nlm.nih.gov/pubmed/22056989
http://dx.doi.org/10.1038/nature10648